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Contemporary evidence on stearidonic acid health - promoting effects
BEATA KRÓL1*, ANNA KIELTYKA-DADASIEWICZ2
*Corresponding author
1. University of Life Sciences in Lublin, Department of Industrial and Medicinal Plants, 15 Akademicka Str., 20-950 Lublin, Poland
2. Research & Science Innovation Center, 4 Tarasowa Str., 20-819 Lublin, Poland

KEYWORDS: Fatty acid, omega-3, SDA, cardiovascular disease, cancers, diabetes, inflammatory diseases.

ABSTRACT: Omega-3 (n-3) fatty acids are widely recognized as an important factor regulating a number of human disorders. The main source of omega-3 fatty acids) in the diet is seafood, especially cold-water fishes (EPA and DHA) and some vegetable oils (ALA). Because the dietary intake of omega-3 fatty is insufficient, other dietary options are being sought. Research has shown that stearidonic acid (SDA), present in some vegetable oils, may increase the EPA levels. The main objective of this article is to review current knowledge regarding the impact of stearidonic acid on human health. A number of studies have demonstrated that SDA has a beneficial effect on several diseases, such as hypertriglyceridemia, cardiovascular and inflammatory diseases, diabetes, and some types of cancer.


INTRODUCTION

Fatty acids are compounds with a diverse chemical structure and many important biological functions. With regard to prevention and treatment of several diseases, special attention should be given to omega-3 acids, which are necessary for the proper functioning of the human body (1). They influence the regulation of the cardiovascular system, blood pressure, plasma triglyceride concentration, immune response and inflammatory processes, cancer development, regulation of hormones and neuromediators, gene expression, kidney functioning, and the proper functioning of neurons and the retina (2). The main source of omega-3 fatty acids in the diet is seafood, especially cold-water fishes and some vegetable oils (e.g. linseed oil, camelina oil). Due to low consumption of seafood products and insufficient dietary supplementation with marine fish oils, an effective and safe source of oil rich in omega-3 that could be an alternative to fish oils are currently being sought (3).

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